How does an effervescent medicine work?

EFFERVESCENT REMEDY

TdF suggestedMatheus Albuquerque Photograph Daniel Ozana/Studio Oz edition Felipe van Deursen

The formula for the effervescent tablet can vary depending on the remedy, but the basic ingredients are usually an organic acid and a carbonate base. The bubble characteristics are the result of tablet contact with water, which generates several chemical reactions. The biggest advantage of this type of medicine is that its active ingredient is absorbed much faster. But he is also an alternative for those who cannot swallow pills. That’s why the industry invested in effervescent versions of products that exist in other formats, such as aspirin and vitamin C. In addition, these dissolved dragees result in a liquid with a pleasant taste, masking the bad taste of some medicines.

BASIC FORMULA

The effervescent tablet is usually the compression of a medicine (such as paracetamol and aspirin) with mixtures of weak organic acids (ascorbic, citric and tartaric acid, for example) and carbonated bases (mainly sodium bicarbonate and sodium carbonate). Water breaks down weak acid molecules in a process known as ionization. This generates electrically charged bits, the ions.

IT’S NOT JUST WATER

Any drink with water will react with the tablet, producing CO2 and therefore bubbles. That is, there will be effervescence, but factors such as viscosity and pH can interfere with the chemical reaction and the final taste. In practice, taking these remedies with teas, juices or sodas does not make much difference.

OH, BUBBLES

Ionization causes the formation of carbonic acid (H2CO3), which is very unstable and decomposes. One of the resulting components is carbon dioxide bubbles. A tip: they are a sign that the chemical reaction is in full swing. That is, the ideal is to wait for the pill to disappear in the water – and not to take it while the bubbling happens, as many believe.

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Do not abuse!

Excessive consumption can cause several problems

A 2013 study from the University of Dundee, in England, indicated that excessive consumption of effervescent drugs can cause hypertension and increase cardiovascular risks, because of the high sodium content. It is always good to remember: before taking any medicine, consult a doctor and read the leaflet

ONE LAST CURIOSITY: As saliva is 99% water, the effervescent effect also works inside the mouth. But, in addition to being slower, you will drool foam

READ TOO

– What happens to the medicine in the stomach?

– How do antipyretic drugs work?

– What is the difference between generic, branded and similar medicine?

Sources Marcelo Polachini, author of the QuimicAtual project and professor of the courses Aeon Vestibulares, Anglo Leonardo da Vinci, Central de Concursos and V8 Bragança Paulista; Honério Coutinho, professor at the Federal University of Espírito Santo (Ufes) and author of the Chemistry Show project

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