Why do some people have different colored eyes?

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Illustrated by: Erika Onodera

It is due to an abnormality called heterochromia. It can either be genetically inherited or acquired through disease or injury. There are two types: the sectoral (two colors in the same eye) and the complete (one eye of each color), and it is even possible to have both types at the same time. All sorts of combinations are possible (blue and green, brown and blue, etc.). The decisive factor is the same as for those who have the same two eyes: the amount of melanin in the iris of the eyeball. This amount is determined by a number of different genes (i.e. Mendel’s First Law does not apply here), such as OCA2 and EYCL3, and these are affected when a person has genetic heterochromia. The phenomenon occurs in less than 1% of the world’s population (and in some dogs and cats). It is harmless, but it can also be caused by some serious diseases like neurofibromatosis.

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WINDOW’S SOUL

Learn how color is determined and learn about possible variations

Brown -Too much melanin and too many melanosomes

Green -Medium amounts of melanin and melanosomes

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Blue – Little melanin and few melanosomes

TYPES OF HETEROCROMY

1) Segmented sector

2) Central sector

3) Complete

4) Complete sector

QUESTION Kaique Rossoni, Colatina, ES

SOURCE Article Genetics of Eye Color, Hudson Alpha Institute for Biotechnology; websites Dráuzio Varela, Saúde Visual and Medicine Net

CONSULTANCY Keila Monteiro de Carvalho, director of the Brazilian Council of Ophthalmology

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